South-West Asia, the most common theories is the world as part of the Middle East. Limits the term is unclear or there is no consensus. South-West Asia, the most common theories is the world as part of the Middle East. Limits the term is unclear or there is no consensus. While South-West Asia, is a geographical term that refers to the part of Asian countries and political units of the Southwest are included.This part of Asia is a large region based on different variables, is comprised of several distinct regions. Study based on cultural and Civilization factors, several regions the region's geopolitical and political units combined and a single political unit that is shared between each of these regions, there is geopolitical hierarchy. In each of the geopolitical regions in South-West Asia, intra-regional competition and competition between regions neighboring a region with no longer there, Therefore this kind of competition is reflected in the behavior of social - cultural and Civilization regions appears.This article is a descriptive - analytic study using a documentation data gathering method, tries to analyze the geopolitical regions South-West Asia and geopolitical relationships prevailing each of these regions is based on cultural and Civilization variables.