India and Israel are in a multilateral long-term relationship with each other. Iran, as a third party, has two different stances with regard to these two countries. On the one, Iranian culture has its root in India and Iranian have longstanding formal and informal relationship with this country; on the other hand, because of the emergence of Israel and the way it treats Muslims it has been known as a usurper since the Islamic Revolution and is regarded as one of Iran's enemies. Relationship between Iran’s enemy and ally can create conditions worthy of study. This study is aimed at evaluating geo-culture policies of Israel in India and its impact on cultural influence of Iran in the Indian subcontinent. This is a descriptive-analytical research, the results of which are obtained based on library studies. The research hypothesis is that expansion of friendly ties between Israel and India could threaten Iran's national interests. Studies have shown that Israel has adopted various policies to reduce the effectiveness of Iran influence in Indian society and limit the influence of Persian culture